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International journal of Immunopathology, allergology, infectology.

The abnormality of the immune status at patients of the pancreatitis and its correction with immunomodulin

Suleymanov S.F.

Buchara State Medical University, Buchara, Uzbekistan

The immune status has been studied at 78 patients with the diagnosis a pancreatitis (34 were with acute pancreatitis (AP) and 44 with a chronic pancreatitis (CP). Control group of comparison consisting of practically healthy 36 persons. Infringements of the immune status are found out in patients AP and CP, especially from the T-link of immunity, and also a pressure humoral a component of immunity. The most essential shifts in functioning immune system are revealed at CP. Inclusion in the scheme of complex treatment patients of a pancreatitis immunomodulin (at AP - 1,0 - 1,2 mg at CP - 1,2 - 1,8 mg on a course of therapy) led to elimination of the expressed T-cellular immunodeficiency in both groups and promoted restoration of some parameters humoral a component of immunity. Immunomodulin possessed medical and immunocorrection action at patients of a pancreatitis to what parameters the index of immunocorrection Êi during therapy testified.

Keywords

Immune status, pancreatitis, immunodeficiency, immunocorrection, immunomodulin.

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Reference

Suleymanov S.F. Immunopathology, allergology, infectology 2008; 1:6-10

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