Antistreptococcal activity of sodium hypochlorite

Korikova S.I., Miklis N.I., Dmitrachenko T.I., Burak I.I.

The list of medicines for local treatment of acute tonsillitis is widespread. Solutions of electrochemical sodium hypochlorite have shown high efficiency at complex treatment of acute tonsillitis. For these purposes the activated solution of electrochemical sodium hypochlorite developed by us is perspective.
The purpose of this work was to study antistreptococcal activity of electrochemical and activated electrochemical solutions of sodium hypochlorite.
Results of the researches have shown, that the minimum bactericidal concentration in attitude of b-hemolytic streptococcus of group A for the solution of electrochemical sodium hypochlorite is the contents of active chlorine 200 mg/dm3, and for the activated electrochemical sodium hypochlorite solution - 150 mg/dm3.
The electrochemical solution of sodium hypochlorite and the activated electrochemical solution of sodium hypochlorite in the minimum bactericidal concentration in the presence of horse serum and without it are characterized by high antimicrobial activity concerning S. pyogenes with the reduction factor more than 5 lg and correspond to requirements of the standard technical legal documentation.
Studied electrochemical and activated electrochemical solutions of sodium hypochlorite with high antistreptococcal activity it is possible to recommend as antiseptics for wide application in medicine.