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International journal of Immunopathology, allergology, infectology.

Immunological parameters in syphilis patients with obvious clinical manifestations

Koshkin S.V., Chermnykh T.V., Zaitseva G.A.

State Budget Educational Institution of Higher Education of the Health Care and Social Development Ministry of the Russian Federation “Kirov State Medical Academy”
1Federal State Institution “Kirov Research Institute of Hematology and Blood Transfusion of the Federal Medical Biological Agency”

The current article analyzes the results of immunological investigations of syphilis patients with obvious clinical symptoms. Dominating changes were insufficiency of cellular immunity, activation of humeral immunity and activation of factors of non-specific resistance. It is suggested that immunological mechanisms take part in pathogenesis of syphilitic alopecia and leukoderma. Illustrations are provided.


Syphilis, manifestations, immunological changes

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Koshkin S.V., Chermnykh T.V., Zaitseva G.A. Immunopathology, allergology, infectology 2014; 1:57-62