Immune disturbances at system and local level at patients with an adenomyosis

Neznamova N.V., Ivanova O.Y., Konoplya A.A., Karaulov A.V., Mal’tseva A.N., Gavriliuk V.P.

Kursk state medical university, Kursk, Russian Federation (305041, Kursk, str. K. Marksa, 3)

The purpose: to establish character of immune disturbances at system and local level at patients with an internal endometriosis (adenomyosis).
Methods: clinical research, definition of indicators of the immune status in a blood plasma both vaginal and cervical washout.
Results: before the beginning of complex standard treatment rising of level of proinflammatory cytokines, activation of system of a complement, a disbalance in the maintenance of antiinflammatory cytokines, regulators of system of a complement and immunoglobulins at system and local level is established. Depression of activity and intensity of a phagocytosis with simultaneous augmentation of activity of oxygen systems of neutrophils is taped. Efficiency of treatment has appeared insufficient that proves necessity of use of effective ways and agents of immune aftertreatment.