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International journal of Immunopathology, allergology, infectology.

Specific methods for the diagnosis of tuberculosis

Prylutskyi O.S., Rohova Yu.D.

Donetsk National Medical University named after Gorky, Donetsk, DPR

In this review we described the modern methods for the diagnosis of tuberculosis and analyzed their advantages and disadvantages. The use of the method is determined by the aim of the study, the patient's age, the presence of comorbidities and other risk factors as well as the diagnostic value and sensitivity of the tests. If the results of Mantoux test are suspicious and positive it is expedient to give the diaskin test that has more high specificity for pathogenic mycobacteria. It is expedient to use only Mantoux test for the selection of persons to be vaccinated with BCG at the age of 2 months. Due to the high cost and complexity of interferon gamma release assays, they should be used only as referent for the present.


Mantoux test, diaskin test, QuantiFERON-TB, tuberculin, tuberculosis, diagnosis, sickness rate, vaccination.

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Prylutskyi O.S., Rohova Yu.D. Immunopathology, allergology, infectology 2015; 3:47-55