Natural autoantibodies in normal and pathological conditions

Myagkova M.A., Morozova V.S., Petrochenko S.N.

Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, Moscow region, Russia.

The review presents new experimental data of domestic and foreign scholars in the field of immunology, which extend the existing ideas about the participation of the antibody in
the mechanisms of homeostasis. Problems concerning the origin and the expression of natural antibodies, natural autoimmunity in human pathology, the role of autoantibodies in regulating physiological reactions and the development of autoimmune disease.