Determination of the main spectrum of allergen sensitization among patiens from Yaroslavl, Russia

Vorontsova I.M., Potayevich Yu.A., Syrovtseva A.A., Sokolova A.V.

Yaroslavl State Medical University of the Ministry of Healthcare of the Russian Federation, Yaroslavl, Russia

The number of patients with allergy increases constantly and there is a tendency of sensitization spectrum widening. It is necessary to know the main causative allergens in different age groups in order to plan clinical examination and treatment. The aim is to determine a sensitization spectrum to the main causative allergens, a frequency of mono– and polysensitization in adults and children with allergy living in Yaroslavl, Russia.
Materials and methods. Meta-analysis of patient’s medical records and their prick-tests results was made. A panel of allergens included house dust mite, pollen (trees, grass and weeds), cat epithelium, dog fur, and molds. There were 79 patients: 41 adults and 38 children.
Results. The number of patients with allergic rhinitis increased with age – up to 81% in adults. The main allergens in children and adults were house dust mite and tree pollen. In children, a group of epidermal allergens was also important. Despite more frequent monosensitization in children, than in adults, there were more polysensitized children than monosensitized inside children group. The most frequent combinations of causative allergens in polysensitized patients were “house dust mite and tree pollen” and “house dust mite and epidermal allergens” (43,33 and 40% respectively).