Immune status of HIV-infected children with acute rhinosinusitis

Narzullaev N.U., Suleymanov S.F.

Abu Ali ibn Sino after named Bukhara State Medical Institute, c. Bukhara, Uzbekistan

The immune status of 25 HIV-infected children with acute rhinosinusitis (ARS) was studied. The control group of comparison consisted from 14 practically healthy persons. In HIV-infected patients with ARS deep infringements of the immune status were revealed, especially in the T-link of immunity and its subpopulations, and also frustration of humoral immunity link, suppression of proinflammatory cytokine IL-10 and increase of proinflammatory IFN-alpha. Under treatment no significant changes were found in the immune status of patients. It is possible to ascertain only positive changes in maintenance of IL-10 and parallel decrease in IFN-alpha in dynamics of treatment.