COVID-19 associated invasive mycoses

Kutsevalova O.U., Antonets A.V., Krylov V.B., Nifantiev N.E., Miroshnichenko D.I., Mikutin A.V.

National Medical Research Center of Oncology, Rostov-on-Don, Russia
Rostov State Medical University, Rostov-on-Don, Russia
N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia
Don State Technical University, Rostov-on-Don, Russia
Rostov Regional Clinical Hospital, Rostov-on-Don, Russia

The COVID-19 pandemic has revealed the new forms of invasive fungal infections. Without timely diagnosis and treatment, mortality reaches 100%. We analyzed 31 observed cases of invasive mucormycosis and aspergillosis in patients with COVID-19 to identify risk factors, the time sequence of the onset of clinical symptoms, and diagnostic features. Major predisposing factors were diabetes mellitus, immunosuppressive therapy, and oncological diseases.