Modern concepts of the pathogenesis of atopic dermatitis

Gorskii V.S., Blyumina V.A.

Peoples` Friendship University of Russia (RUDN University), Moscow, Russia

The article discusses modern ideas about the mechanisms of development of atopic dermatitis. The role of the most significant pathogenetic factors (genetic factors, the influence of epidermal barrier disorders, the role of exogenous factors, immunological disorders, changes in the microbiome of the skin and intestines) is discussed. The results of research as well as data from domestic and foreign publications are presented.