Enzymatic activity of Chryseobacterium arthrospherae bacteria colonizing the respiratory tract of patients with cystic fibrosis

Zubova K.V., Kuznetsova V.A., Kondratenko O.V., Glinskaya E.V.

Saratov National Research State University named after N.G. Chernyshevsky, Saratov
Samara State Medical University of the Ministry of Health of the Russian Federation, Samara

The enzymatic activity of Chryseobacterium arthrospherae bacteria isolated from the respiratory tract of patients with cystic fibrosis was analyzed. The aim of the study was to evaluate the role of enzymes as a virulence factor. The material for the study comprised 20 strains of bacteria obtained from patients across multiple subjects of the Russian Federation. Methods employed various differential diagnostic environments, as well as tablet test systems. The results of the study revealed that most strains of Chryseobacterium arthrospherae bacteria have a wide range of enzymatic activity, which can play a role in pathogenesis, for example, during invasion and colonization. It is advisable to continue studying the bacteria of the genus Chryseobacterium as a potential pathogen, as well as to identify the clinical role of microorganisms in the infection process occurring in the respiratory tract of cystic fibrosis patients.