Microbiocenosis and biological properties of the intestinal microflora from HIV- infection children

Zakharova J.V., Karaulov A.V., Markovskaya A.A., Levanova L.A., Afanasyev S.S., Alyoshkin A.V., Afanasyev M.S.

Aim. Evaluation of intestinal microflora and optimization methods of correction microbiocenosis in HIV-infection children. Materials and methods. 269 strains isolated from intestine of 68 HIV-infection children were used for the study. Isolation and indentification of microorganisms were performed by conventional methods. Factors of colonization in dominant microflora, virulent factors in minor associative microsymbionts and interactions between microorganisms were determined. Results. It is revealed that the opportunistic microorganisms from associates an antagonism activity for dominant microflora were characterized. Reduce level of Bifidobacteria and Lactobacillus in intestine correlated with adhesive and acidforming activity was shown. In associative symbiosis opportunistic microorganisms factors of virulent were high expressioned. Obtained data pathogenic basis of development endogens infection HIV-infection children are provided.