Clinical and diagnostic features of whooping cough in children in Omsk

Puzyreva L.V., Gashina E.A., Paimanova L.N., Golovanova N.V., Schaefer E.P., Lobova E.F., Sabaeva N.A.

Omsk State Medical University, Omsk, Russia
City Children's Clinical Hospital No. 3, Omsk, Russia

Whooping cough continues to be a pressing morbidity problem in children, and the risk of severe and complicated courses increases with age under one year. The aim of the study was to evaluate the anamnestic, clinical and diagnostic manifestations of whooping cough in children in different age groups.
Materials and methods. A retrospective, selective case study of 114 children with whooping cough who were treated at the children's infectious diseases hospital of the Children's City Clinical Hospital № 3 was conducted for the period from September 2023 to January 2024.
Results. According to our study, predominantly unvaccinated children (78.9%) were hospitalized with a diagnosis of whooping cough. Among the sick children immunized against whooping cough, children over three years of age who received acellular whooping cough vaccine predominated. Clinically, a typical course was observed in all groups. Mostly, inpatient treatment was required for children under one year of age (42.9%). In these patients, the disease was often severe and led to development of complications. Diagnosis of whooping cough was carried out using the bacteriological method, polymerase chain reaction and enzyme-linked immunosorbent assay.