The modern condition of alternative methods of cholera prevention and treatment

Ivanova I.A., Filippenko A.V., Omelchenko N.D., Tyurina A.V., Gaevskaya N.E.

Federal Service for Surveillance in the Sphere of Consumers Rights Protection and Human Welfare, Rostov-on-Don, Russia

The incidence of cholera in the world remains at a high level. The existing potential risk of the spread of this infection to countries of different continents indicates the need for alternative integrated approaches to the treatment and prevention of cholera. The review aims to analyze current data and assess the potential of various compounds as alternative therapies and preventives for cholera. Information obtained from Russian and foreign sources over the past decade, including PubMed, Scopus, Web of Science, Google Scholar and RSCI, is used to study the efficiency of various substances and drugs against the causative agent of cholera. The potential of probiotics, bacteriophages and polyclonal and monoclonal specific antibodies is studied with consideration of enteral and parenteral administration.