Have the clinical features of cypress pollinosis changed over 33 years of observation?

Belyaeva S.N., Pirogova M.E., Solovyova E.A.

I.M. Sechenov Academic Research Institute of Physical Methods of Treatment, Medical Climatology and Rehabilitation of the Health Ministry of Crimean Republic, Yalta, Russia
Simferopol Polyclinic № 4 of the Health Ministry of Crimean Republic, Simferopol, Russia

Introduction. Since the first studies of cypress pollinosis in residents of the South Coast of Crimea (SCC), its course has undergone certain changes.
The aim of this study was to identify changes in the clinical symptoms of cypress pollinosis in residents of the SCC over 33 years of observation.
Materials and methods. Two groups of local residents of the South Coast of Crimea were identified: the first group had symptoms of hay fever diagnosed in 1992, the second group had symptoms of hay fever identified in 2024. Sensitization to cypress pollen in both groups was confirmed by skin tests and detection of specific IgE using the ImmunoCAP method. Statistical processing and analysis of the obtained data were performed using the Statistica-12 program, Pearson's χ2 criterion, Fisher's test (two-tailed test) and the nonparametric Mann-Whitney test.
Results and discussion. A comparison of clinical and anamnestic data was conducted in groups 1 and 2 of residents of the SCC, and changes during the observation period were analyzed.
Conclusions. During the observation period, allergic rhinitis and conjunctivitis remained prevalent in patients with cypress hay fever, while a decreasing incidence of bronchial asthma, an absence of allergic dermatoses, and an increased age of symptom onset were observed. Sensitization to cypress pollen was confirmed in predisposed individuals who lived on the Southern Coast of Crimea for a long time.